Co-Op - Discovery Biology -Cardiovascular (Fall 2025)
Company: Disability Solutions
Location: Brisbane
Posted on: October 19, 2024
Job Description:
Working with UsChallenging. Meaningful. Life-changing. Those
aren't words that are usually associated with a job. But working at
Bristol Myers Squibb is anything but usual. Here, uniquely
interesting work happens every day, in every department. From
optimizing a production line to the latest breakthroughs in cell
therapy, this is work that transforms the lives of patients, and
the careers of those who do it. You'll get the chance to grow and
thrive through opportunities uncommon in scale and scope, alongside
high-achieving teams rich in diversity. Take your career farther
than you thought possible.Bristol Myers Squibb recognizes the
importance of balance and flexibility in our work environment. We
offer a wide variety of competitive benefits, services and programs
that provide our employees with the resources to pursue their
goals, both at work and in their personal lives. Read more:
.Position Summary The Immunology and Cardiovascular Thematic
Research Center (ICV TRC) is focused on discovering and developing
novel therapeutics to treat immunological and cardiovascular
diseases. The Cardiovascular Discovery group within the ICV-TRC
seeks to understand disease pathophysiology to enable target
identification that will allow the discovery of novel therapeutics
for patients with cardiovascular diseases.BMS seeks a highly
motivated, creative, and collaborative Molecular and/or Cellular
Biologist to join our Cardiovascular Discovery group. This person
will support research efforts to discover and develop novel
therapies for the treatment of serious cardiovascular disease,
including genetic cardiomyopathies and heart failure. The
successful candidate will work collaboratively with teams in Cell
Biology, Biochemistry/Biophysics, Lead Discovery and Optimization
(LDO) among others to support BMS's Cardiovascular Research and
Early Discovery efforts. Research will be aimed at establishment
and validation of cellular models for novel therapeutic targets,
and development of cellular assays for screening therapeutics. The
candidate will be a highly motivated individual with extensive
experience in iPSC handling and cardiomyogenic differentiation,
molecular and cellular biology techniques, gene expression
modulation and cellular assay development. Previous experience with
engineered heart tissue (EHT) formation and screening methodologies
will be highly desirable. This position provides the exciting
opportunity to be a part of and grow with a key discovery function
within the CV Discovery group.Key Responsibilities
- Work independently and collaboratively in cross-functional
teams to advance state-of-the-art molecular techniques for disease
mechanisms and drug development research.
- Demonstrate technical proficiency, scientific creativity, and
independent thought in suggesting experimental design and research
strategy.
- Broad range of molecular and cellular biology methods to
interrogate and validate iPSC disease models and novel therapeutic
targets/hypotheses.
- Support iPSC-CM differentiation and manufacturing towards
generating disease models and supporting screening campaigns.
- Work closely with our discovery biology and LDO teams to
develop and optimize cell-based biological and validation
assays.
- Support development of EHTs from various iPSC-CM disease lines
towards generating of appropriate CV disease models.
- Ability to stay current with scientific literature and
technologies and interpret literature results in light of new
findings.
- Prepare reports, publications and present to cross-functional
teams and senior management.Qualifications & Experience Basic
Qualifications:
- Bachelor's Degree with 5+years of academic or industry
experience or
- Master's Degree with 3+ years of academic or industry
experience or
- PhD and No years of experience
- Must be available to work from July 2025 to December
2025Preferred Qualifications:
- Extensive hands-on experience in cell biology and cellular
assays including iPSC maintenance and cardiogenic differentiation
is required
- Documented experience with methodologies for functional
assessment of iPSC-CMs (contractility, electrophysiology, metabolic
properties, and other) is strongly preferred
- Familiarity with development and application of EHTs for CV
disease modeling using healthy and mutant iPSC lines is highly
desirable
- Strong experience with cellular and molecular biology
methodologies including cytotoxicity assays, gene expression
analysis, RNAi technologies, immunocytochemistry is needed. If you
come across a role that intrigues you but doesn't perfectly line up
with your resume, we encourage you to apply anyway. You could be
one step away from work that will transform your life and career.
Uniquely Interesting Work, Life-changing CareersWith a single
vision as inspiring as Transforming patients' lives through
science--- , every BMS employee plays an integral role in work that
goes far beyond ordinary. Each of us is empowered to apply our
individual talents and unique perspectives in an inclusive culture,
promoting diversity in clinical trials, while our shared values of
passion, innovation, urgency, accountability, inclusion and
integrity bring out the highest potential of each of our
colleagues.On-site Protocol BMS has a diverse occupancy structure
that determines where an employee is required to conduct their
work. This structure includes site-essential, site-by-design,
field-based and remote-by-design jobs. The occupancy type that you
are assigned is determined by the nature and responsibilities of
your role: Site-essential roles require 100% of shifts onsite at
your assigned facility. Site-by-design roles may be eligible for a
hybrid work model with at least 50% onsite at your assigned
facility. For these roles, onsite presence is considered an
essential job function and is critical to collaboration,
innovation, productivity, and a positive Company culture. For
field-based and remote-by-design roles the ability to physically
travel to visit customers, patients or business partners and to
attend meetings on behalf of BMS as directed is an essential job
function. BMS is dedicated to ensuring that people with
disabilities can excel through a transparent recruitment process,
reasonable workplace accommodations/adjustments and ongoing support
in their roles. Applicants can request a reasonable workplace
accommodation/adjustment prior to accepting a job offer. If you
require reasonable accommodations/adjustments in completing this
application, or in any part of the recruitment process, direct your
inquiries to . Visit to access our complete Equal Employment
Opportunity statement. BMS cares about your well-being and the
well-being of our staff, customers, patients, and communities. As a
result, the Company strongly recommends that all employees be fully
vaccinated for Covid-19 and keep up to date with Covid-19 boosters.
BMS will consider for employment qualified applicants with arrest
and conviction records, pursuant to applicable laws in your area.If
you live in or expect to work from Los Angeles County if hired for
this position, please visit this page for important additional
information: Any data processed in connection with role
applications will be treated in accordance with applicable data
privacy policies and regulations.
Keywords: Disability Solutions, Danville , Co-Op - Discovery Biology -Cardiovascular (Fall 2025), Other , Brisbane, California
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